The Journal of

  Background : Denture stomatitis is a common inflammatory complication of the candidiasis seen under the maxillary denture, which is observed in 70% of cases following a chronic trauma. Candidia species particularly Candida albicans are known as one of endogenous etiologic agent of denture stomatitis that may cause systemic opportunistic infection in immunosupressed subjects. The aim of present study was to determine frequency of oral candidiasis in patients with complete denture referring to Yazd dentistry school.

  Methods : Totally 109 patients with denture referring to Yazd School of Dentistry were participated in the current cross-sectional descriptive study. The designed questionnaire was first completed and then the clinical assessment was carried out by the oral disease specialist in dental unit. Sample was collected from the oral mucosa and used for a direct smear and culture and finally the results were analyzed by using SPSS 13 soft ware.

  Result : There wasn't any statistical significant differences between the Colonization of Candida on denture and sex (P=0.32). Statistical data showed a higher colonization of Candida albicans on the oral mucosal surface of denture users with oral disorder compared with denture users without oral complication (P=0.002). Tongue and maxillary denture showed the highest Candida colonization in current study .

  Conclusion : Results of current study confirmed the major role of Candida in the incidence of denture stomatitis. The oral and denture hygiene and disinfection of denture can decrease Candida colonization and oral candidiasis in denture users.