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Introduction: Gastric cancer is the second leading cause of cancer-related mortality worldwide and is yet increasing in Asian countries such as Iran. Despite using chemotherapy for the treatment, its 5-year survival is only about 20%. Thus, the complementary therapy and prevention are the main efforts for its control. In this review article, we attempt to describe the eefective strategies for prevention of gastric cancer. Methods: This is a review article the related articles of which were taken from internet and scientisic journals. The databases such as Medline,Web of Science, Science Direct, Google Scholar, and Springer were explored for the purpose. Results: The prevention programs included clinical studies using the strategies to delay progression of cancer. Thus, several studies have indicated that the world risk of gastric cancer is in an inverse relationship with social, economic and nutritional situations. One of the most important of them is using proper dietary (High antioxidant diet) strategy. Frresh fruit and vegetables may reduce the risk of gastric cancer and dysplasia because they reduce the effects of oxidative stress in cells. Conclusion: The risk of stomach cancer in people with proper life style whose diets are rich in fruit and vegetables may be decreased but smoking and unhealthy diet are associated with increased risk of gastric cancer.

Keywords: Gastric cancer, Prevention, Risk factor, Diet

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