Intriduction: Health and food safety is one of the most important factors in the prevention of food-borne diseases, However, due to insufficient knowledge and incorrect function, many people suffer from food poisoning. Therefore, this study aimed to investigate the effect of education on knowledge, attitude and practice of students in medical university towards food poisoning.
 
Methods: This is a quasi-experimental study that was carried out on 100 students of Yazd University of Medical Sciences, Iran. The subjects were randomly divided into two groups of experimental and control, each of them included 50 students. The data collection tool was a questionnaire consisted of four parts that validity and reliability was approved. Participants in the two groups filled out the questionnaire before intervention. educational program was accomplished in experimental group by educational booklet and  the data of the two groups were collected  after two months of intervention.
 
 
Results: The mean score of knowledge, attitude and practice of experimental group after intervention significantly increased (P=0.001), There was significant difference between the attitude variable and level of education )P=0.007). A significant positive correlation among variables of knowledge, attitude and practice was observed as well.
 
 
Conclusion: Educational intervention is effective on the rate of knowledge, attitude and practice of students. According to the high prevalence of food poisoning that happens frequently due to living in dormitories or traveling, it is necessary to implement various and constant educational programs.