Volume 14, Number 5 (1-2016)                   TB 2016, 14(5): 29-37 | Back to browse issues page


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Fallahzadeh H, Golshanzadeh Z, Mozafari H, Momayezi M. Meta-analysis of studies on the effect of vitamin D supplementation on blood glucose, lipid profile and inflammatory markers in patients with diabetes. TB. 2016; 14 (5) :29-37
URL: http://tbj.ssu.ac.ir/article-1-1900-en.html

MS.c hahid Sadoughi University of Medical Sciences yazd. , zohregolshan@yahoo.com
Abstract:   (871 Views)

Introduction: Vitamin D deficiency and type 2 diabetes are both common diseases. Numerous studies have examined the relationship between the two. The purpose of this study was to investigate the effect of vitamin D supplementation on glycemic status, lipid profile and inflammatory markers in patients with diabetes.

Method: Type of systematic review and meta-analysis, which is actually a review on the studies available. Beginning a search extensively on electronic resources English, including EMBASE, Web of science, Medline Scopus and Who and electronic resources Persian including SID and Google scholar for diabetes-related research papers do.

Result: The test of heterogeneity, studies with significant heterogeneity in vitamin D, HOMA-IR and insulin sensitivity were the random effects model was used and the mean difference and 95% confidence intervals between the two groups in the vitamin D , 1.87 and (-5.49,9.23), HOMA-IR 0.09 and (-.023,0.05) and insulin sensitivity, 0.24 and (-0.75,0.26), respectively.

Discussion: The overall results of this study showed that the meta-analysis, vitamin D and insulin sensitivity in diabetic patients is effective and HOMA-IR is not effective on patients with diabetes.

Full-Text [PDF 288 kb]   (288 Downloads)    
Type of Study: Applicable | Subject: Special
Received: 2013/04/28 | Accepted: 2013/06/10 | Published: 2016/01/18

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